Polyquad (Preservative used in Systane and Tears Naturale)
IN BRIEF
Polyquad is the preservative Alcon uses in its popular contact lens solutions as well as its artificial tear products.
DISCUSSION
WHAT THE MANUFACTURER SAYS
"According to investigators in a clinical study, '...there is potential for certain biguanide-containing MPS systems to invoke significant corneal staining. Switching to non-PHMB based regimens will eliminate this complication in most instances.'"
"SYSTANE® is preserved with POLYQUAD®, while REFRESH TEARS* is preserved with PURITE*. Both preservatives have shown to be safe and have been used in numerous ophthalmic formulations for several years."